(R)-(-) Epichlorohydrin
R-epichlorohydrin
CAS: 51594-55-9
Molecular Formula: C3H5ClO
(R)-(-) Epichlorohydrin - Names and Identifiers
(R)-(-) Epichlorohydrin - Physico-chemical Properties
| Molecular Formula | C3H5ClO |
| Molar Mass | 92.52 |
| Density | 1.180g/mLat 20°C(lit.) |
| Melting Point | -48°C |
| Boling Point | 114°C(lit.) |
| Specific Rotation(α) | 34 º (589nm, c=1, MeOH) |
| Flash Point | 33 °C |
| Water Solubility | insoluble |
| Vapor Presure | 10 mm Hg ( 16.6 °C) |
| Vapor Density | 3.29 (vs air) |
| Appearance | Liquid |
| Color | Clear colorless to very pale yellow |
| Merck | 14,3532 |
| BRN | 1420785 |
| Storage Condition | 2-8°C |
| Explosive Limit | 21% |
| Refractive Index | n20/D 1.438(lit.) |
| Physical and Chemical Properties | Boiling point 92-93 °c (360mm Hg). |
| Use | For the synthesis of chiral intermediates and chiral drugs |
(R)-(-) Epichlorohydrin - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R45 - May cause cancer R10 - Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R43 - May cause sensitization by skin contact |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2023 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | RR0427000 |
| TSCA | Yes |
| HS Code | 29103000 |
| Hazard Class | 6.1 |
| Packing Group | II |
(R)-(-) Epichlorohydrin - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| uses | various chiral pharmaceutical intermediates. Chiral structural unit, its epoxy functional group can react with a variety of nucleophiles to generate chloroethanol; used to synthesize chiral morpholine and dioxane through Mitsunobu diol cyclization; used as a chiral structural unit for enantioselective synthesis of trans -2,4-disubstituted piperidine for the synthesis of chiral intermediates and chiral drugs |
| spontaneous combustion temperature | 772 °F |
Last Update：2024-04-10 22:29:15
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